Can You Develop Sucrose Intolerance?
Sucrose Intolerance caused by Congenital Sucrase-Isomaltase Deficiency (CSID) is a rare disorder that causes a reduction in the activity of the digestive enzymes sucrase and isomaltase. Some individuals are diagnosed with this type of sugar intolerance early in life during infancy, while others are diagnosed later in life, even in adulthood.
Individuals who have Sucrose Intolerance caused by CSID are unable or have limited ability to tolerate sucrose-containing foods, including grains, certain fruits and vegetables, or any product containing table sugar. When an individual with Sucrose Intolerance caused by CSID consumes sucrose, gastrointestinal symptoms – stomach pain, chronic diarrhea, gas, and bloating – occur.
Some individuals experience these symptoms immediately after sucrose consumption while other have a delayed response. Infants who develop Sucrose Intolerance caused by CSID often experience these same symptoms, but they are typically much more severe.
Getting an appropriate CSID diagnosis can be challenging, since the symptoms of CSID mimic the gastrointestinal symptoms of other more common digestive conditions. For example, infants and children with chronic diarrhea may be misdiagnosed as having toddler’s diarrhea, irritable bowel syndrome, and even parasites. If treatment is pursued for these misdiagnoses and the symptoms are not alleviated, the child should be referred to a gastroenterologist for further evaluation.
An individual can also develop Sucrose Intolerance due to other conditions. This type of Sucrose Intolerance is called acquired Sucrose Intolerance. For example, if an individual has an infection or inflammation that affects the brush border of the gastrointestinal tract, Sucrose Intolerance may develop. For these individuals, sucrase activity should return to normal once the intestinal inflammation or infection is successfully treated and the enzyme-producing function of the brush border returns.
Because CSID is an inherited, genetic condition, individuals with Sucrose Intolerance caused by CSID are born with CSID. For some, CSID may be misdiagnosed early in life, and the correct diagnosis may not be made until later in life. If you believe you or your child has Sucrose Intolerance caused by CSID, take our quiz* and speak with your physician.
*This quiz is not a diagnostic.
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