I Have CSID – What Are the Odds My Child Will Too?
By: Dr. Partha Nandi
There are some people living with a digestive condition called Sucrose Intolerance caused by Congenital Sucrase-Isomaltase Deficiency (CSID). It’s a genetic condition that affects the body’s ability to digest certain sugars. Because people with CSID lack the fully functional enzymes needed to properly break down and digest sucrose (sugars), eating foods too high in sucrose increases health risks and leads to problems ranging from unpleasant to extremely serious symptoms, such as gas, bloating, diarrhea, and abdominal pain. Naturally, parents or parents-to-be want to know if their children will inherit this uncommon and challenging condition.
Is CSID hereditary?
CSID can be passed down to your children, but the likelihood depends on the parental gene structure. Each person has two copies of each gene, one copy inherited from the father and the other copy inherited from the mother. Each gene copy can be different and is either recessive or dominant. Think of the dominant genes as overpowering the recessive genes. With dominant genes, only one gene copy has to carry a mutation for a condition to be passed along to offspring. Mutations in the gene associated with CSID are recessive.
If one or both of the parents have a gene with a mutation associated with CSID, then there is a chance that the child will inherit the condition. However, typically, two copies of the recessive gene are needed for the child to experience symptoms of CSID.
Stay vigilant and know your options.
If CSID is present in your biological family, be observant and ready to recognize any relevant symptoms. If a family member is suffering from symptoms associated with CSID, he or she should see a doctor and get tested. If diagnosed with a Sucrose Intolerance caused by CSID, management options are available.
Maintaining healthy eating habits is a must for anyone living with CSID. These criteria might require extra planning and attention, but avoiding dietary sources of sucrose and starch sugars reduces unwanted symptoms and keeps your condition under control.
Pharmaceutical therapy is available. Consult with your physician or registered dietitian to determine whether a pharmaceutical therapy is appropriate for you.
Living with CSID has its challenges, but it’s nothing that you, or your child, can’t handle. Help protect your family’s health by remaining vigilant. If you notice symptoms that might be indicative of Sucrose Intolerance caused by CSID, remain calm and confident knowing that you’re prepared to make informed choices and take any necessary action.
The views, opinions, and positions expressed by the authors and those providing comments on these blogs are theirs alone, and do not necessarily reflect the views, opinions, or positions of sucroseintolerance.com. Dr. Nandi is a consultant of QOL Medical, LLC.
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