What Is Sucrose Intolerance?

The digestive enzymes sucrase and isomaltase assist in an individual’s ability to digest certain sugars. The absence or low levels of these two enzymes disrupts the digestive process, and can cause symptoms upon eating food containing sugars. This rare disorder is called Genetic Sucrase-Isomaltase Deficiency (GSID) and is equally prevalent in males and females. This disorder is also known as SI Deficiency, Disaccharide Intolerance and Congenital Sucrase-Isomaltase Deficiency (CSID).
To learn more, see below.

What Is Sucrose Intolerance?

The digestive enzymes sucrase and isomaltase assist in an individual’s ability to digest certain sugars. The absence or low levels of these two enzymes disrupts the digestive process, and can cause symptoms upon eating food containing sugars. This rare disorder is called Genetic Sucrase-Isomaltase Deficiency (GSID) and is equally prevalent in males and females. This disorder is also known as SI Deficiency, Disaccharide Intolerance and Congenital Sucrase-Isomaltase Deficiency (CSID).

Sucrase deficiency can also occur due to other disorders, including those that cause irritation or inflammation of the intestinal lining, such a celiac disease or infection. In these cases, the sucrase level should return to normal once the primary cause is resolved and does not require the same type of treatment as GSID. However, for a patient with GSID, the deficiency is caused by a variation in the person’s genetics and will likely always be present. To learn more, see below.

  • GSID Symptoms

    Are you experiencing chronic diarrhea, chronic abdominal pain and gassiness? Have you ruled out celiac disease and/or lactose intolerance? Learn More About GSID Symptoms

  • GSID Causes

    The absence or low levels of sucrase and isomaltase disrupts the digestive process, and can cause symptoms upon eating food containing sugars. Find out More About GSID Causes

  • GSID Testing and Diagnosis

    A gastroenterologist will perform a routine analysis of patient well-being, including a physical examination, clinical history, family history, and diet history, and may order tests to determine the exact diagnosis. Get Information About Testing and Diagnosis

  • GSID Treatment Options

    The diagnosis of Genetic Sucrase-Isomaltase Deficiency (GSID) can be missed, especially if a patient has mild, nonspecific symptoms. Explore How to Effectively Communicate With Your Doctor

  • Patient Stories

    View stories from patients providing insights into their experiences with Genetic Sucrase-Isomaltase Deficiency (GSID). Watch Patient Stories

  • Take the Sugar Intolerance Quiz

    Take our FREE quiz to assess if you may have sugar intolerance (GSID). Take Quiz